NephroTDM

Session
Model-informed therapeutic drug monitoring for kidney transplantation and nephrology. Choose a drug, enter the dosing and any measured concentrations, and the app estimates the patient’s exposure with its uncertainty and shows what a different dose would do. Everything runs locally in your browser: nothing you enter is sent or processed online. The only copy is an autosave in this browser.
1 Patient & covariates 2 Dosing & samples 3 Forecast 4 Explore dose (optional)

1 Patient & covariates

Drug / PK model
Therapeutic window: AUC₀–12h – change
The target is the AUC over a 12-hour dosing interval at steady state (AUC₀–12h). Regimens with another interval are compared as their 12-hour equivalent: AUC₁₂ = AUC₀–ₓ × 12/ₓ.

2 Dosing schedule & measured concentrations

Measured concentrations

3 Forecast

Inputs changed. Press “Run forecast” to update.
Advanced fitting options
How to read these results

    4 Explore dose

    Run a forecast in card 3 first. This explorer reuses that fit's own parameters.