Therapeutic drug monitoring — eculizumab · ravulizumab · crovalimab

Model-informed TDM and PK forecasting · all computation local, no data leaves this device
1 Drug & weight 2 Add doses & samples 3 Run forecast 4 Explore regimen (optional)

1 Drug & patient

Trough target change

2 Dosing schedule & measured concentrations

Measured concentrations

Assay settings (LLOQ, error multiplier)
Default 1 — leave unchanged unless your lab advises otherwise.

3 Forecast

Inputs changed — press “Run forecast” to update.
Individual = incorporates this patient's own measured levels · Population = model only, no patient data yet · red points = measurements · dashed amber line = target · faint dotted amber = a projected future dose, not yet given.
Advanced fitting options
How to read these results
  • Band (5–95%): 90% plausible range for the true concentration — it does not include assay error, so a future measured value may fall outside it.
  • P(trough > target): chance the true trough stays above your target, at your chosen dates.
  • Median trough [5–95%]: the same distribution in µg/mL.

4 Regimen explorer

Run a forecast in card 3 first — this explorer reuses that fit's own parameters.